The focus areas of this project are genomic cancer research, research into the phenotypic effects of the composition of the human microbiome, and the field of infection biology in the context of dynamic mutation development of the SARS-CoV-2 and other pathogenic genomes, including new technology development in these areas. In the long term, the project…
Synthetic immunology allows to analyze and modify central processes of immune recognition with highest precision at the single cell level. Using DNA nanotechnology and microfluidics, precision and high-throughput tools for characterizing and programming immune cells are being developed. This yields completely new insights for the development of diagnostic and therapeutic methods such as genetically modified…
Quantitative molecular analyses of the tissue using spatially-resolved Multi-Omics-techniques provide completely new insights into cellular functions in health and disease, and into the cellular response to environmental influences and drug treatment. However, there is currently a lack of interdisciplinary platforms for using spatially-resolved omics-technologies in the form of robust, scalable analysis methods in pre- and…
Early Clinical Trials (ECTs) are of central importance in the development and implementation of current preclinical concepts in precision medicine (personalized medicine), e.g., in the application of innovative drugs, RNA- or cell-based therapies, new drugs or brain stimulation treatments for mental disorders, but also in the development of low-invasive diagnostics, e.g., liquid biopsies from blood…
Innovative methods of analysis based on artificial intelligence and machine learning have found their way into all research areas and are already enabling transformative developments in health research. A major challenge in order to increase the potential of AI approaches is the linking of AI procedures with large-scale annotated and medically meaningful data sources. By…
The Health + Life Science Alliance Heidelberg Mannheim is supported by the State of Baden-Württemberg as part of its Innovation Campus strategy. The Innovation Campus is financed through state funds approved by the State Parliament of Baden-Württemberg.
