Family relationships as health-promoting factors in old age: Investigating markers of biological aging and health outcomes in a large cohort of older adults
Examining effects of methylome epigenetics
Using state-of-the-art methylation arrays, we have generated full methylome epigenetic information for nearly 200 individuals and their long-term partners. This data has been combined with phenotypic and demographic information to provide a comprehensive dataset that includes information on methylation, disease and health outcomes, lifestyle factors and nutrition, risk behaviours, biological samples, and cognitive and sensory assessments. Work is currently ongoing to identify how the pair relationships between individuals affect their epigenetic similarity, how risk behaviours may affect methylation changes in behaviour-engaged individuals, and how these behaviours and profiles may be reflected in their non-behaviour-engaged partner.