Health + Life Science Alliance Heidelberg Mannheim

Hubert Senanu Ahor, Medical Faculty Mannheim, Heidelberg University
Investigating the critical role of iron metabolism in the failing heart with spatial and single-cell metabolomics
Steven Dooley, Medical Faculty Mannheim, Heidelberg University + Martina Muckenthaler, Medical Faculty Heidelberg, Heidelberg University

Kaili Fu, EMBL
Quantifying the impact of drug combination treatments of colorectal cancer on the composition and metabolic functions of the gut microbiota
Michael Zimmermann, EMBL + Tianzuo Zhan, Medical Faculty Mannheim, Heidelberg University

Steffanie Heindl, EMBL
Decrypting the cancer neuroscience of brain tumors with integrated correlative intravital microscopy and high-resolution spatial multi-omics
Sinema Saka, EMBL + Varun Venkataramani, Medical Faculty Heidelberg, Heidelberg University

Despoina Kiousi, EMBL
Dissecting the regulation of colibactin production and genotoxicity in E. coli
Nassos Typas, EMBL + Jens Puschhof, DKFZ

Pedro Pablo Rojas, Heidelberg University
Human and AI alignment: Learning generalization principles from cognitive maps
Georgia Koppe, Heidelberg University + Gordon Feld, ZI

Stefan Schrod, EMBL
Towards an in silico model of the cell – perturbations, time and experimental design
Oliver Stegle, EMBL + Britta Velten, Heidelberg University

Nikolaus Watson, EMBL
Micronuclei degradation and cancer genome evolution
Jan Korbel, EMBL + Elmar Schiebel, Heidelberg University

Bettina Welz, EMBL
Understanding temperature sensitivity and robustness of development using
single-cell transcriptomics in genetically diverse medaka strains
Michael Dorrity, EMBL + Duncan Odom, DKFZ

Jack Whitehead, Heidelberg University
Cryogenic super-resolution correlative light and electron microscopy of Influenza A Virus
Petr Chlanda, Heidelberg University + Julia Mahmid, EMBL

Ruri Yamaguchi, DKFZ
Characterization of the liver microbiome in hepatocellular carcinoma (HCC)
Mathis Heikenwälder, DKFZ + Andreas Teufel, Medical Faculty Mannheim, Heidelberg University

Alexander Aivazidis, EMBL

Dynamical causal modelling of gene regulation and cellular trajectories in neural organoids

Oliver Stegle, EMBL + Lars Steinmetz, EMBL + Moritz Mall, Medical Faculty Heidelberg, Heidelberg University

Zahra Haider, Medical Faculty Heidelberg, Heidelberg University
Molecular profiling of liquid biopsies for brain tumor diagnostics and monitoring of treatment response
Felix Sahm, Medical Faculty Heidelberg, Heidelberg University + David Jones, DKFZ

Sabrina Lewis, Medical Faculty Heidelberg, Heidelberg University
Using spatial omics to study the effects of combinatorial drug therapies in tumour biopsies
Denis Schapiro, Medical Faculty Heidelberg, Heidelberg University + Peer Fischer, Heidelberg University

Jan Fabio Nickels, DKFZ
Revealing mechanisms of chromatin domain organization and epigenetic gene regulation
Karsten Rippe, DKFZ + Simon Anders, Heidelberg University

Priyanka Pant, Medical Faculty Heidelberg, Heidelberg University
Deciphering the role of RNA granules vs. missplicing in RBM20 cardiomyopathy; will the real culprit please stand up?
Maarten van den Hoogenhof, Medical Faculty Heidelberg, Heidelberg University + Lars Steinmetz, EMBL

Jose Augusto Pochapski, ZI
Shared and distinct cellular and molecular mechanisms of drug addictions
Rainer Spanagel, ZI + Andreas Draguhn, Medical Faculty Heidelberg, Heidelberg University

Lukas Scheiderer, Medical Faculty Heidelberg, Heidelberg University
Understanding the role of kinesin in HSP on a molecular level using MINFLUX tracking
Rebecca Schüle-Freyer, Medical Faculty Heidelberg, Heidelberg University + Timo Zimmermann, EMBL

Lea Weber, DKFZ
Dynamics of somatic mosaicism in stem cell systems: From data to models
Thomas Höfer, DKFZ + Anna Marciniak, Heidelberg University

Martin Würtz, EMBL
Understanding microtubule organisation by the augmin complex in space and time
Sebastian Eustermann, EMBL + Elmar Schiebel, Heidelberg University + Stefan Pfeffer, Heidelberg University

Céline Zheng-Gérard, Heidelberg University
Structural and functional characterisation of the potassium channel TASK-1 in health and disease
Cristina Paulino, Heidelberg University + Constanze Schmidt, Medical Faculty Heidelberg, Heidelberg University

Eleanor Burgess, Heidelberg University
Microcapsules for immunotherapy of solid tumors
Adelheid Cerwenka, Medical Faculty Mannheim, Heidelberg University + Christine Selhuber-Unkel, Heidelberg University

Hairuo Dang, EMBL
Exploring the mechanism of pronuclear migration in mouse and human oocytes
Jan Ellenberg, EMBL + Thomas Strowitzki, Medical Faculty Heidelberg, Heidelberg University

Esra Oktay, Heidelberg University
VIROGAMI – Synthetic virology meets DNA/RNA origami
Dirk Grimm, Heidelberg University + Kerstin Göpfrich, Heidelberg University and MPI for medical research

Roger Ottenheijm, Medical Faculty Heidelberg, Heidelberg University
New Ca2+ entry and release channels in platelets – relevance for thrombosis and inflammation
Marc Freichel, Medical Faculty Heidelberg, Heidelberg University + Daniel Dürschmied, Medical Faculty Mannheim, Heidelberg University

Changgyun Park, Medical Faculty Heidelberg, Heidelberg University
Integrative analyses of drug responses in tumor organoids of brain metastases
Christel Herold-Mende, Medical Faculty Heidelberg, Heidelberg University + Peter Lichter, DKFZ

Zahra Rezaei, Medical Faculty Heidelberg, Heidelberg University
Using MALDI-MS Imaging to determine insecticide cellular localization and potential as malaria-transmission blocking interventions Victoria Ingham, Medical Faculty Heidelberg, Heidelberg University + Carsten Hopf, Medical Faculty Mannheim, Heidelberg University

Jakob Rosenbauer, Medical Faculty Mannheim, Heidelberg University Multi-level data integration to predict the immune therapy response in glioma Michael Platten, Medical Faculty Mannheim, Heidelberg University + Benedict Brors, DKFZ

Amritha Sathyanarayanan, Medical Faculty Mannheim, Heidelberg University
Using Single Cell RNA-sequencing and Spatial Transcriptomics to Elucidating the Ovarian Cancer Tumor Microenvironment in Patients treated with Immune Checkpoint Inhibitors and PARP inhibitors
Frederic Marmé, Medical Faculty Mannheim, Heidelberg University + Benedict Brors, DKFZ

Andrea Zanotti, DKFZ
General and cell type-specific mechanisms for the coupling of protein uptake and lysosomal catabolism
Wilhelm Palm, DKFZ + Matias Simons, Medical Faculty Heidelberg, Heidelberg University

Katharina Zirngibl, Medical Faculty Heidelberg,  Heidelberg University
Understanding regulation of differentiation from multi-omics single-cell assays
Simon Anders, Heidelberg University + Ana Martin-Villalba, DKFZ

Maja Bencun, Medical Faculty Heidelberg, Heidelberg University
Functional characterization of uORF-encoded microproteins in cardiomyocytes
Christoph Dieterich, Medical Faculty Heidelberg, Heidelberg University + Rebecca Wade, Heidelberg University

Aylin Camgöz, DKFZ 
Oncogenic roles of PRDM16 in ST-EPN-ZFTA ependymomas
Marcel Kool, DKFZ + Magdalena Laugsch, Medical Faculty Heidelberg, Heidelberg University

Rafael Cardoso, DKFZ
Discovery and evaluation of non-invasive tests and risk models for personalized colorectal cancer screening
Hermann Brenner, DKFZ + Nuh Rahbari, Medical Faculty Mannheim, Heidelberg University

Ines Castro, Medical Faculty Heidelberg, Heidelberg University
The Nuclear Pore Complex as a site for genomic transcription and splicing
Marina Lusic, Medical Faculty Heidelberg, Heidelberg University + Sinem Saka, EMBL

Florian Constanty, Medical Faculty Heidelberg, Heidelberg University
Dissecting the cardiac regenerative microenvironment using spatial OMICs
Arica Beisaw, Medical Faculty Heidelberg, Heidelberg University + Chi-Chung Wu, Medical Faculty Mannheim, Heidelberg University

Taniya Chakraborty, Heidelberg University
Bottom-up assembly of a macrophage-mimicking synthetic cell
Selhuber-Unkel, Heidelberg University + Kerstin Göpfrich, MPI, Heidelberg University

Quinten Ducarmon, EMBL
Discovery of novel gut bacterial carcinogenesis mechanisms
Georg Zeller, EMBL + Eran Elinav, DKFZ

Charles Dussiau, EMBL
Integrative analysis of single cell omics with cellular and functional features of ageing at a whole organ level using machine learning
Judith Zaugg, EMBL + Michael Milsom, DKFZ

Büşra Erarslan-Uysal, Medical Faculty Heidelberg, Heidelberg University
Characterizing genomic structural variation and leukemogenesis in Shwachman-Diamond-Syndrome
Joachim Kunz, Medical Faculty Heidelberg, Heidelberg University + Jan Korbel, EMBL

Nir Fulman, Heidelberg University
Interdisciplinary research platform “Urban nature experience, biodiversity and mental health”
Alexander Zipf + Marcus Koch + Gerd Hoefele, Heidelberg University + Andreas Meyer-Lindenberg, ZI

Marie Jacobovitz, EMBL
Plasticity of nuclear cycling in response to the environment
Gautam Dey, EMBL + Markus Ganter, Heidelberg University

Nicolai Karcher, EMBL
Towards personalized microbiome-informed immunosuppressive therapy in transplant medicine
Michael Zimmermann, EMBL + Burkhard Tönshoff + David Czock, Medical Faculty Heidelberg, Heidelberg University

Suzan Kors, Heidelberg University
A molecular and ultrastructural analysis of mitotic organelle remodeling and of organelle interactions during mitosis
Anne Schlaitz, Heidelberg University + Yannick Schwab, EMBL

Florian Marx, Medical Faculty Heidelberg, Heidelberg University
Multiplex serology to identify novel biomarkers for tuberculosis
Claudia Denkinger, Medical Faculty Heidelberg, Heidelberg University + Tim Waterboer, DKFZ

Svenja Müller, ZI
Molecular principles underlying the effects of prenatal maternal stress on placenta and neurodevelopment: from a human longitudinal cohort to mechanistic insight
Stephanie Witt, ZI + Alexander Aulehla, EMBL

Maria Lucia Pigazzini, EMBL
Unraveling the emerging link between structural centrosome aberrations and cancer
Niccolò Banterle, EMBL + Ingrid Hoffmann, DKFZ

Daniela Ramirez Butavand, Heidelberg University
Training the sleeping brain: effects of high intensity training on sleep-dependent brain plasticity in major depression
Simon Steib, Heidelberg University + Gordon Feld, ZI

Fredrika Rajer, EMBL
Quantifying the effect of long-term antibiotic prophylaxis in infants on the pediatric microbiome and the development of antibiotic resistance
Michael Zimmermann, EMBL + Christan Gille + Burkhard Toenshoff + Alexander Dalpke, Medical Faculty Heidelberg, Heidelberg University

Vladimir Ryabov, Medical Faculty Mannheim, Heidelberg University
Role of inflammation in fully humanized and immunologically active 3D bone marrow models of healthy and neoplastic hematopoiesis
Daniel Nowak, Medical Faculty Mannheim, Heidelberg University + Marieke Essers, DKFZ

Petr Smirnov, EMBL 
Merging histopathology imaging and genome sequencing using machine learning to discover fundamental properties and translational opportunities of tumors with chromothripsis
Wolfgang Huber, EMBL + Aurelie Ernst, DKFZ

Joshua Stevenson-Hoare, DKFZ
Linking Hyperscanning in EEG and fMRI measures for studying  social interactions
Hermann Brenner, DKFZ + Beate Ditzen, Medical Faculty Heidelberg, Heidelberg University + Judith Zaugg, EMBL

De-en Sun, MPI
Spying on brain tumors with chemogenetic integrators
Kai Johnsson, MPI + Frank Winkler, DKFZ

Matthias Wagner, Medical Faculty Heidelberg, Heidelberg University
GPI-anchored surface proteins of protozoan parasites as targets for therapeutic antibodies
Friedrich Frischknecht, Medical Faculty Heidelberg, Heidelberg University + Nina Papavasiliou + Hedda Wardemann, DKFZ